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dc.contributor.advisorGarzón Ruiz, Mauriciospa
dc.contributor.authorGarzón Ruiz, Mauricio
dc.contributor.authorEscobar Lux, Martha Patricia
dc.contributor.authorPineda Betancur, Catalina
dc.contributor.authorGomez Santofimio, Liliana
dc.contributor.authorAcosta, Rocio
dc.coverage.spatialMedicinaspa
dc.date.accessioned2017-01-26T20:21:19Z
dc.date.accessioned2019-12-30T19:07:57Z
dc.date.available2017-01-26T20:21:19Z
dc.date.available2019-12-30T19:07:57Z
dc.date.issued2014
dc.identifier.urihttp://hdl.handle.net/10654/14961
dc.description.abstractEl Trastorno por Estrés Postraumático (TEPT) es una patología que se puede desarrollar en respuesta a la exposición a una situación traumática como una guerra. En el presente estudio, se tomó una muestra de diez militares expuestos a trauma en guerra y se dividieron en dos grupos iguales: SITEPT (cumple criterios TEPT) y NOTEPT (no cumple criterios TEPT). Ambos grupos fueron sometidos a diez pruebas neuropsicológicas y a tres pruebas de imagen cerebral: Resonancia Nuclear Magnética (RNM), Tractografía de Tensor de Difusión y Tomografía Computarizada de Emisión Monofotónica (SPECT). Este sondeo se realizó para describir patrones de perfusión sanguínea cerebral y evaluar los tractos de sustancia blanca. Se esperaba entonces encontrar alteraciones a nivel de la sustancia blanca durante la aparición de sintomatología aguda de TEPT para correlacionarla con las funciones mentales superiores. Luego de realizarse el sondeo propuesto a dos pacientes SITEPT y a dos NOTEPT durante 2015, se confirmó la hipótesis. Sin embargo, en 2016 de los veintitrés pacientes valorados con trauma de guerra, ninguno cumplió criterios para incluirse en el estudio propuesto. Finalmente, el estudio no se completó debido al déficit de la muestra. No obstante, este déficit en el diagnóstico de TEPT en guerra, invita a estudiar otro tipo de psicopatologías en la población militar y las intervenciones correspondientes.spa
dc.formatpdfspa
dc.language.isospaspa
dc.publisherUniversidad Militar Nueva Granadaspa
dc.titleCaracterización de la perfusión cerebral por spect con tractografía de sustancia blanca y correlación neuropsicológica en trastorno por estrés postraumático con trauma de guerraspa
dc.typeinfo:eu-repo/semantics/bachelorThesisspa
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.subject.lembESTRES POSTRAUMATICOspa
dc.subject.lembTRAUMA PSIQUICOspa
dc.subject.lembPSICOPATOLOGIAspa
dc.subject.lembNEUROPSICOLOGIAspa
dc.publisher.departmentFacultad de Medicinaspa
dc.type.localTrabajo de gradospa
dc.description.abstractenglishPost-traumatic Stress Disorder (PTSD) is a pathology that can be developed as a response to a traumatic event exposure as is the war. In this study, a sample of ten soldiers exposed to war trauma was taken and divided into two equal groups: YES-PTSD (meet criteria to PTSD) and NO-PTSD (do not meet criteria to PTSD). Both groups were subjected to ten neuropsychological tests and three cerebral imaging tests: Magnetic Resonance Imaging (MRI), Diffusion Tensor Tractography and Single Photon Emission Computed Tomography (SPECT). This survey was made to describe cerebral blood perfusion patterns and to assess white matter tracts. It was expected to be found white matter impairment during the onset of PTSD acute symptoms to be correlated with higher mental functions. In this way, after the proposed exploration to two YES-PTSD soldiers and two NO-PTSD soldiers during 2015, the hypothesis was confirmed. However, from twenty-three soldiers with war trauma evaluated in 2016, none met criteria to be included in the proposed study. Finally, this study could not be completed due to the sample deficit. Yet, this deficit in war PTSD diagnosis, invites to consider other types of psychopathologies in military population and their corresponding interventions.eng
dc.title.translatedCharacterization of cerebral perfusion by spect with white matter tractography and neuropsychological correlation in post-traumatic stress disorder with war traumaspa
dc.subject.keywordsPost-traumatic Stress Disorderspa
dc.subject.keywordswar traumaspa
dc.subject.keywordsSPECTspa
dc.subject.keywordsTensor Tractographyspa
dc.subject.keywordsneuropsychological testsspa
dc.publisher.programPsiquiatríaspa
dc.creator.degreenameEspecialista en Psiquiatríaspa
dc.relation.references1. American Psychiatric Association (1994). Diagnostic and statistical manual of mental disorders (3ª ed.). Washington: Autor.spa
dc.relation.references2. American Psychiatric Association (2013). Diagnostic and statistical manual of mental disorders (5ª ed.). Washington: Autor.spa
dc.relation.references3. Brown, T.A., Campbell, L.A., Lehman, C.L., Grisham, J.R. y Mancill, R.B. Current and lifetime comorbidity of the DSM-IV anxiety and mood disorders in a large clinical sample. Journal of Abnormal Psychology. 2001;110:585-599spa
dc.relation.references4. Bryant, R.A., Moulds, M.L. y Guthrie, R.M. Acute Stress Disorder Scale: A self-report measure of acute estrés dis-order. Psychological Assessment.2000;12:61-68.spa
dc.relation.references5. Ozer, E.J., Best, S.R., Lipsey, T.L. y Weiss, D.S. Predictors of posttraumatic stress disorder and symptoms in adults: A meta-analysis. Psychological Bulletin. 2003;129:52-73.spa
dc.relation.references6. Gershuny, B.S., Cloitre, M. y Otto, M.W. Peritraumatic dissociation and PTSD severity: Do event related fears about death and control mediate their relation? Behaviour Research and Therapy. 2003;41:157-166spa
dc.relation.references7. Yehuda, R., Marshall, R., Penkower, A. y Wong, C.M. (2002). Pharmacological treatments of post-traumatic stress disorder. En P. Nathan y J. Gorman (Eds.), A guide to treatments that work (2ª ed., pp. 411-445). Nueva York: Oxford Univer-sity Press.spa
dc.relation.references8. Sadock, B.J., Sadock, V.A., 2005. Kaplan and Sadock's Comprehensive. Textbook of Psychiatry, 8th ed. Lippincott Williams and Wilkins.)spa
dc.relation.references9. Paunovic, N. (1997). Exposure therapy for post-traumatic stress disorder: Its relative efficacy, limitations and optimal appli-cation. Scandinavian Journal of Behaviour Therapy, 26, 54-69.spa
dc.relation.references10. Frans, Ö., Rimmö, P.-A., Åberg, L. y Fredrikson, M. (2005). Trauma exposure and post-traumatic stress disorder in the general population. Acta Psychiatrica Scandinavica, 111, 291-299.spa
dc.relation.references11. ESEMeD/MHEDEA 2000 Investigators (2004). Prevalence of mental disorders in Europe: Results from the ESEMeD Euro-pean Study of Epidemiology of Mental Disorders (ESEMeD) project. Acta Psychiatrica Scandinavica, 109 (suppl. 420), 21–27.spa
dc.relation.references12. Rauch SL, Whalen PJ, Shin LM, McInerney SC, Macklin ML, Lasko NB, Orr SP, Pitman RK. Exaggerated amygdala response to masked facial stimuli in posttraumatic stress disorder: a functional MRI study. Biol Psychiatry. 2000 May 1;47(9):769-76.spa
dc.relation.references13. Sagaspe P, Schwartz S, Vuilleumier P. Fear and stop: a role for the amygdala in motor inhibition by emotional signals. Neuroimage. 2011 Apr 15;55(4):1825-35.spa
dc.relation.references14. New AS, Fan J, Murrough JW, Liu X, Liebman RE, Guise KG, Tang CY, Charney DS. A functional magnetic resonance imaging study of deliberate emotion regulation in resilience and posttraumaticstress disorder. Biol Psychiatry. 2009 Oct 1;66(7):656-64.spa
dc.relation.references15. Toths B. Cicchetti L.(1998). Physiological evidence concerning the importance of amygdaloid nuclear region in the integration of circulating functions and emotion in man. Science 129: 949-950spa
dc.relation.references16. Davis M. (1992). The role of amygdala in fear and anxiety. Annual Reviews of Neuroscience; 15: 353-375.spa
dc.relation.references17. Gould F., Woolley M. (2000). Neurobiological and clinical consequences of stress: From normal adaptation to PTSD; New York Raven Press; 239-269.spa
dc.relation.references18. McEwen R.J. (2000). Activation of the hippocampus in normal humans: A functional anatomical study of memory. Proceedings of the National Academy of Science; 89: 1837-1841spa
dc.relation.references19. Nelson M, Carver R. (2000). Changes of brain anatomy in patients with posttraumatic stress disorder: a pilot magnetic resonence imaging study. Psychiatry Res; 58: 259-264.spa
dc.relation.referencesBremner, J. D. et al.(1995). MRI-based measurement of hippocampal volume in patients with combat-related posttraumatic stress disorder. Am. J. Psychiatry 152, 973–981.spa
dc.relation.references21. Moustafa AA, Gilbertson MW, Orr SP, Herzallah MM, Servatius RJ, Myers CE. A model of amygdala-hippocampal-prefrontal interaction in fear conditioning and extinction in animals. Brain Cogn. 2013 Feb;81(1):29-43.spa
dc.relation.references22. De Bellis MD, Hall J, Boring AM, Frustaci K, Moritz G. A pilot longitudinal study of hippocampal volumes in pediatric maltreatment-related posttraumatic stress disorder. Biol Psychiatry. 2001 Aug 15;50(4):305-9.spa
dc.relation.references23. Ressler KJ. Amygdala activity, fear, and anxiety: modulation by stress. Biol Psychiatry. 2010 Jun 15;67(12):1117-9.spa
dc.relation.references24. Yin Y, Jin C, Hu X, Duan L, Li Z, Song M, Chen H, Feng B, Jiang T, Jin H, Wong C, Gong Q, Li L. Altered resting-state functional connectivity of thalamus in earthquake-spa
dc.subject.proposalTrastorno por estrés postraumáticospa
dc.subject.proposalSPECTspa
dc.subject.proposaltrauma de guerraspa
dc.subject.proposalRNM cerebralspa
dc.subject.proposaltractografia por difusiónspa
dc.subject.proposalpruebas neuropsicológicasspa


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