Mostrar el registro sencillo del ítem
Caracterización de la perfusión cerebral por spect con tractografía de sustancia blanca y correlación neuropsicológica en trastorno por estrés postraumático con trauma de guerra
dc.contributor.advisor | Garzón Ruiz, Mauricio | spa |
dc.contributor.author | Garzón Ruiz, Mauricio | |
dc.contributor.author | Escobar Lux, Martha Patricia | |
dc.contributor.author | Pineda Betancur, Catalina | |
dc.contributor.author | Gomez Santofimio, Liliana | |
dc.contributor.author | Acosta, Rocio | |
dc.coverage.spatial | Medicina | spa |
dc.date.accessioned | 2017-01-26T20:21:19Z | |
dc.date.accessioned | 2019-12-30T19:07:57Z | |
dc.date.available | 2017-01-26T20:21:19Z | |
dc.date.available | 2019-12-30T19:07:57Z | |
dc.date.issued | 2014 | |
dc.identifier.uri | http://hdl.handle.net/10654/14961 | |
dc.description.abstract | El Trastorno por Estrés Postraumático (TEPT) es una patología que se puede desarrollar en respuesta a la exposición a una situación traumática como una guerra. En el presente estudio, se tomó una muestra de diez militares expuestos a trauma en guerra y se dividieron en dos grupos iguales: SITEPT (cumple criterios TEPT) y NOTEPT (no cumple criterios TEPT). Ambos grupos fueron sometidos a diez pruebas neuropsicológicas y a tres pruebas de imagen cerebral: Resonancia Nuclear Magnética (RNM), Tractografía de Tensor de Difusión y Tomografía Computarizada de Emisión Monofotónica (SPECT). Este sondeo se realizó para describir patrones de perfusión sanguínea cerebral y evaluar los tractos de sustancia blanca. Se esperaba entonces encontrar alteraciones a nivel de la sustancia blanca durante la aparición de sintomatología aguda de TEPT para correlacionarla con las funciones mentales superiores. Luego de realizarse el sondeo propuesto a dos pacientes SITEPT y a dos NOTEPT durante 2015, se confirmó la hipótesis. Sin embargo, en 2016 de los veintitrés pacientes valorados con trauma de guerra, ninguno cumplió criterios para incluirse en el estudio propuesto. Finalmente, el estudio no se completó debido al déficit de la muestra. No obstante, este déficit en el diagnóstico de TEPT en guerra, invita a estudiar otro tipo de psicopatologías en la población militar y las intervenciones correspondientes. | spa |
dc.format | spa | |
dc.language.iso | spa | spa |
dc.publisher | Universidad Militar Nueva Granada | spa |
dc.title | Caracterización de la perfusión cerebral por spect con tractografía de sustancia blanca y correlación neuropsicológica en trastorno por estrés postraumático con trauma de guerra | spa |
dc.type | info:eu-repo/semantics/bachelorThesis | spa |
dc.rights.accessrights | info:eu-repo/semantics/openAccess | spa |
dc.subject.lemb | ESTRES POSTRAUMATICO | spa |
dc.subject.lemb | TRAUMA PSIQUICO | spa |
dc.subject.lemb | PSICOPATOLOGIA | spa |
dc.subject.lemb | NEUROPSICOLOGIA | spa |
dc.publisher.department | Facultad de Medicina | spa |
dc.type.local | Trabajo de grado | spa |
dc.description.abstractenglish | Post-traumatic Stress Disorder (PTSD) is a pathology that can be developed as a response to a traumatic event exposure as is the war. In this study, a sample of ten soldiers exposed to war trauma was taken and divided into two equal groups: YES-PTSD (meet criteria to PTSD) and NO-PTSD (do not meet criteria to PTSD). Both groups were subjected to ten neuropsychological tests and three cerebral imaging tests: Magnetic Resonance Imaging (MRI), Diffusion Tensor Tractography and Single Photon Emission Computed Tomography (SPECT). This survey was made to describe cerebral blood perfusion patterns and to assess white matter tracts. It was expected to be found white matter impairment during the onset of PTSD acute symptoms to be correlated with higher mental functions. In this way, after the proposed exploration to two YES-PTSD soldiers and two NO-PTSD soldiers during 2015, the hypothesis was confirmed. However, from twenty-three soldiers with war trauma evaluated in 2016, none met criteria to be included in the proposed study. Finally, this study could not be completed due to the sample deficit. Yet, this deficit in war PTSD diagnosis, invites to consider other types of psychopathologies in military population and their corresponding interventions. | eng |
dc.title.translated | Characterization of cerebral perfusion by spect with white matter tractography and neuropsychological correlation in post-traumatic stress disorder with war trauma | spa |
dc.subject.keywords | Post-traumatic Stress Disorder | spa |
dc.subject.keywords | war trauma | spa |
dc.subject.keywords | SPECT | spa |
dc.subject.keywords | Tensor Tractography | spa |
dc.subject.keywords | neuropsychological tests | spa |
dc.publisher.program | Psiquiatría | spa |
dc.creator.degreename | Especialista en Psiquiatría | spa |
dc.relation.references | 1. American Psychiatric Association (1994). Diagnostic and statistical manual of mental disorders (3ª ed.). Washington: Autor. | spa |
dc.relation.references | 2. American Psychiatric Association (2013). Diagnostic and statistical manual of mental disorders (5ª ed.). Washington: Autor. | spa |
dc.relation.references | 3. Brown, T.A., Campbell, L.A., Lehman, C.L., Grisham, J.R. y Mancill, R.B. Current and lifetime comorbidity of the DSM-IV anxiety and mood disorders in a large clinical sample. Journal of Abnormal Psychology. 2001;110:585-599 | spa |
dc.relation.references | 4. Bryant, R.A., Moulds, M.L. y Guthrie, R.M. Acute Stress Disorder Scale: A self-report measure of acute estrés dis-order. Psychological Assessment.2000;12:61-68. | spa |
dc.relation.references | 5. Ozer, E.J., Best, S.R., Lipsey, T.L. y Weiss, D.S. Predictors of posttraumatic stress disorder and symptoms in adults: A meta-analysis. Psychological Bulletin. 2003;129:52-73. | spa |
dc.relation.references | 6. Gershuny, B.S., Cloitre, M. y Otto, M.W. Peritraumatic dissociation and PTSD severity: Do event related fears about death and control mediate their relation? Behaviour Research and Therapy. 2003;41:157-166 | spa |
dc.relation.references | 7. Yehuda, R., Marshall, R., Penkower, A. y Wong, C.M. (2002). Pharmacological treatments of post-traumatic stress disorder. En P. Nathan y J. Gorman (Eds.), A guide to treatments that work (2ª ed., pp. 411-445). Nueva York: Oxford Univer-sity Press. | spa |
dc.relation.references | 8. Sadock, B.J., Sadock, V.A., 2005. Kaplan and Sadock's Comprehensive. Textbook of Psychiatry, 8th ed. Lippincott Williams and Wilkins.) | spa |
dc.relation.references | 9. Paunovic, N. (1997). Exposure therapy for post-traumatic stress disorder: Its relative efficacy, limitations and optimal appli-cation. Scandinavian Journal of Behaviour Therapy, 26, 54-69. | spa |
dc.relation.references | 10. Frans, Ö., Rimmö, P.-A., Åberg, L. y Fredrikson, M. (2005). Trauma exposure and post-traumatic stress disorder in the general population. Acta Psychiatrica Scandinavica, 111, 291-299. | spa |
dc.relation.references | 11. ESEMeD/MHEDEA 2000 Investigators (2004). Prevalence of mental disorders in Europe: Results from the ESEMeD Euro-pean Study of Epidemiology of Mental Disorders (ESEMeD) project. Acta Psychiatrica Scandinavica, 109 (suppl. 420), 21–27. | spa |
dc.relation.references | 12. Rauch SL, Whalen PJ, Shin LM, McInerney SC, Macklin ML, Lasko NB, Orr SP, Pitman RK. Exaggerated amygdala response to masked facial stimuli in posttraumatic stress disorder: a functional MRI study. Biol Psychiatry. 2000 May 1;47(9):769-76. | spa |
dc.relation.references | 13. Sagaspe P, Schwartz S, Vuilleumier P. Fear and stop: a role for the amygdala in motor inhibition by emotional signals. Neuroimage. 2011 Apr 15;55(4):1825-35. | spa |
dc.relation.references | 14. New AS, Fan J, Murrough JW, Liu X, Liebman RE, Guise KG, Tang CY, Charney DS. A functional magnetic resonance imaging study of deliberate emotion regulation in resilience and posttraumaticstress disorder. Biol Psychiatry. 2009 Oct 1;66(7):656-64. | spa |
dc.relation.references | 15. Toths B. Cicchetti L.(1998). Physiological evidence concerning the importance of amygdaloid nuclear region in the integration of circulating functions and emotion in man. Science 129: 949-950 | spa |
dc.relation.references | 16. Davis M. (1992). The role of amygdala in fear and anxiety. Annual Reviews of Neuroscience; 15: 353-375. | spa |
dc.relation.references | 17. Gould F., Woolley M. (2000). Neurobiological and clinical consequences of stress: From normal adaptation to PTSD; New York Raven Press; 239-269. | spa |
dc.relation.references | 18. McEwen R.J. (2000). Activation of the hippocampus in normal humans: A functional anatomical study of memory. Proceedings of the National Academy of Science; 89: 1837-1841 | spa |
dc.relation.references | 19. Nelson M, Carver R. (2000). Changes of brain anatomy in patients with posttraumatic stress disorder: a pilot magnetic resonence imaging study. Psychiatry Res; 58: 259-264. | spa |
dc.relation.references | Bremner, J. D. et al.(1995). MRI-based measurement of hippocampal volume in patients with combat-related posttraumatic stress disorder. Am. J. Psychiatry 152, 973–981. | spa |
dc.relation.references | 21. Moustafa AA, Gilbertson MW, Orr SP, Herzallah MM, Servatius RJ, Myers CE. A model of amygdala-hippocampal-prefrontal interaction in fear conditioning and extinction in animals. Brain Cogn. 2013 Feb;81(1):29-43. | spa |
dc.relation.references | 22. De Bellis MD, Hall J, Boring AM, Frustaci K, Moritz G. A pilot longitudinal study of hippocampal volumes in pediatric maltreatment-related posttraumatic stress disorder. Biol Psychiatry. 2001 Aug 15;50(4):305-9. | spa |
dc.relation.references | 23. Ressler KJ. Amygdala activity, fear, and anxiety: modulation by stress. Biol Psychiatry. 2010 Jun 15;67(12):1117-9. | spa |
dc.relation.references | 24. Yin Y, Jin C, Hu X, Duan L, Li Z, Song M, Chen H, Feng B, Jiang T, Jin H, Wong C, Gong Q, Li L. Altered resting-state functional connectivity of thalamus in earthquake- | spa |
dc.subject.proposal | Trastorno por estrés postraumático | spa |
dc.subject.proposal | SPECT | spa |
dc.subject.proposal | trauma de guerra | spa |
dc.subject.proposal | RNM cerebral | spa |
dc.subject.proposal | tractografia por difusión | spa |
dc.subject.proposal | pruebas neuropsicológicas | spa |
Archivos en el ítem
Este ítem aparece en la(s) siguiente(s) colección(ones)
-
Psiquiatría [14]