Tandem Reactions in Organic Synthesis: The Artistic Approach in Modern Organic Chemistry
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Barrera-Adame, Diana Astrid
Álvarez-Caballero, Juan Manuel
Coy-Barrera, Ericsson David
Universidad Militar Nueva Granada
tandem, domino, michael, aldol, multicomponent, chiral auxiliary.
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The rise of the processes involving sequential reactions (tandem) is mainly due to its advantages. Although it is required high inventiveness and synthetic knowledge, this provides synthetic pathways and processes whose atomic economy is high, in addition to being inexpensive, since it can avoid many purification and separation steps during synthesis. They are also environmentally generous, avoiding the use and production of toxic substances, and the possibility to build complex molecules with high stereoselectivity. This review aims to give a few examples, from existing plethora so far, allowing illustrating and clarifying aspects related to processes involving sequential reactions with an inventiveness that borders on a level that it would be considered as art.
Enlace al recursohttps://revistas.unimilitar.edu.co/index.php/rfcb/article/view/2041
FuenteRevista Facultad de Ciencias Básicas; Vol. 8, Núm. 2 (2012); 292-309
Revista Facultad de Ciencias Básicas; Vol. 8, Núm. 2 (2012); 292-309