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dc.creatorYurgaky S., James M.
dc.creatorBastidas, Alirio
dc.creatorConta, Jhon A.
dc.creatorMontaña, Jaime A.
dc.creatorArredondo G., Ana María
dc.date2011-06-30
dc.identifierhttps://revistas.unimilitar.edu.co/index.php/rmed/article/view/1275
dc.identifier10.18359/rmed.1275
dc.descriptionEl síndrome de apnea hipoapnea obstructiva del sueño (SAHOS) es una enfermedad frecuente que afecta alrededor del 5 % de la población general y a casi la mitad de los pacientes obesos. La asociación de SAHOS con obesidad ha sido bien establecida desde que fue descrito por primera vez; durante los últimos años ha sido creciente la producción literaria que asocia la hipoxemia con un incremento de la enfermedad cardiovascular y metabólica, las cuales finalmente originan un mayor riesgo cardiovascular en los pacientes afectados no necesariamente obesos. Debido a la presencia de hipoxemia secundaria a la obstrucción mecánica del flujo aéreo que se encuentra en los pacientes afectados por el síndrome de apnea hipoapnea obstructiva del sueño, se desencadenan eventos fisiopatogénicos tales como la liberación de radicales libres, la disminución de la expresión de algunas enzimas importantes para el clivaje del colesterol y la producción de óxido nítrico y el aumento en la producción de mediadores inflamatorios que generan disrupción de vías metabólicas y endocrinológicas, lo cual ocasiona un incremento en el riesgo de sufrir diabetes mellitus, resistencia a la insulina, hipertensión arterial, obesidad y dislipidemia aterogénica.es-ES
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dc.languagespa
dc.publisherUniversidad Militar Nueva Granadaes-ES
dc.relationhttps://revistas.unimilitar.edu.co/index.php/rmed/article/view/1275/1012
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dc.rightsDerechos de autor 2015 Revista Medes-ES
dc.sourceRevista Med; Vol. 19 No. 1 (2011): january - june; 37-44en-US
dc.sourceRevista Med; Vol. 19 Núm. 1 (2011): enero - junio; 37-44es-ES
dc.source1909-7700
dc.source0121-5256
dc.subjectapnea del sueño obstructivaes-ES
dc.subjectSíndrome X metabólicoes-ES
dc.subjecthipertensiónes-ES
dc.titleMás allá del molesto ronquido: síndrome de apnea obstructiva del sueño y su peligrosa asociación con el síndrome metabólicoes-ES
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion


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