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Control del Ciclo menstrual con el uso de anticonceptivos orales en pacientes con síndrome de ovario poliquístico (SOP), resultados en el servicio Endocrinología- Ginecológica del Hospital Militar Central en un periodo de ocho años 2019-2020
dc.contributor.advisor | Diaz Yamal, Ivonne | |
dc.contributor.author | Usta, Carla Patricia | |
dc.contributor.author | Avila Suarez, Luis Miguel | |
dc.contributor.other | Lopez, Diana Marcela | |
dc.coverage.spatial | Hospital Militar Nueva Granada | spa |
dc.coverage.temporal | 2013-2020 | spa |
dc.date.accessioned | 2021-12-30T15:07:53Z | |
dc.date.available | 2021-12-30T15:07:53Z | |
dc.date.issued | 2021-11-24 | |
dc.identifier.uri | http://hdl.handle.net/10654/39882 | |
dc.description.abstract | Introducción: El Síndrome de ovario poliquístico (SOP), es una patología con un espectro clínico dinámico que afecta alrededor del 15% de las mujeres en edad reproductiva (1); así mismo la presentación de irregularidades del ciclo menstrual constituye el principal motivo de consulta de las pacientes. De igual forma, muchas de estas pacientes asisten por presentación de trastornos cutáneos como el acné, signos de hiperandrogenismo como el hirsutismo, aumento de peso y en menor grado, aquellas con deseo de fertilidad (2). Por esta razón consideramos importante determinar el control del ciclo menstrual en las pacientes pertenecientes al régimen especial de las fuerzas militares valoradas en el Hospital Militar Central en los servicios de Ginecología, Endocrinología y dermatología. Metodología: Se realizó un estudio observacional descriptivo de corte transversal, en el cual se tomó como población a aquellas pacientes atendidas en el Hospital Militar Central, en el periodo comprendido entre junio de 2013 y diciembre de 2020, con registros consignados en sistema Dinámica Gerencial Hospitalaria, las cuales se sometieron a criterios de inclusión y exclusión. Se consignó la información en REDCap 11.3.4 - ©️ 2021, con posterior traslado de los datos a Excel para el pertinente análisis estadístico. Resultados: Aquellas pacientes con uso de terapia hormonal con base en progestinas obtuvieron una alta tasa de control del ciclo menstrual, con resultados levemente superiores respecto al uso de terapia dual con Metformina, de igual forma los trastornos cutáneos presentaron mejoría con dichas terapias en razones considerables. La fertilidad en el grupo de estudio se pudo evaluar con la presentación de embarazos inesperados. Conclusiones: En nuestra población, el motivo de consulta más común fue la irregularidad del ciclo menstrual con repercusiones en la calidad de vida de las pacientes. Es fundamental conocer de esta patología, su prevalencia, manifestaciones clínicas, las diferentes formas de presentación, para ofrecer una derivación temprana y un tratamiento oportuno. | spa |
dc.description.tableofcontents | Introduccion Metodologia Resultados Conclusiones Discusion | spa |
dc.format.mimetype | applicaction/pdf | spa |
dc.language.iso | spa | spa |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.title | Control del Ciclo menstrual con el uso de anticonceptivos orales en pacientes con síndrome de ovario poliquístico (SOP), resultados en el servicio Endocrinología- Ginecológica del Hospital Militar Central en un periodo de ocho años 2019-2020 | spa |
dc.rights.accessrights | info:eu-repo/semantics/openAccess | spa |
dc.type.local | Tesis/Trabajo de grado - Monografía - Especialización | spa |
dc.description.abstractenglish | Polycystic ovary syndrome is a pathology with a dynamic spectrum that affects around 15% of women of reproductive age (1), likewise the presentation of irregularities of menstrual pattern is one of the main, if not the main reason of consultation of the patients of suffer this disease. Similarly, many of these patients attend due to the presentation of clinical symptoms such as hirsutism and acne, and to a lesser degree, those with a desire for fertility or improvement of anthropometric parameters (2). For this reason, we consider it is important to determine the control of the menstrual cycle in patients belonging to the special regime of the Military Forces assessed at the Central Military Hospital. Design: An observational descriptive cross-sectional study was carried out, in which patients treated at the Central Military Hospital were taken as the population, in the period of 2013 and December 2020, with records consigned in the Dinamica Gerencial Hospitalaria System ®️ , they were subjected to criteria of inclusion and exclusion eliminating selection biases, subsequently the information was recorded Using REDCap 11.3.4 - ©️ 2021. Results: Those patients with the use of progestin-based hormonal therapy had a high rate of control of menstrual pattern, with was slightly better results than the use of dual therapy with Metformin. In the same way, skin symptoms improved with these therapies for considerable reasons. Fertility in the study group could be assessed with the presentation of unexpected pregnancies. Conclusions: In our population, the most common reason for consultation was the irregularity of the menstrual cycle with repercussions on the quality of life of the patients. It is essential to know about this pathology, its prevalence, clinical manifestations, the different forms of presentation, to offer an early referral and timely treatment. Key words: Hirsutism, Obesity, Anovulation, polycystic ovaries and Infertility | spa |
dc.title.translated | Control of the menstrual cycle with the use of oral contraceptives in patients with Polycystic Ovary Syndrome (PCOS), results in the Endocrinology-Gynecology service of the Central Military Hospital in a period of eight years 2019-2020 | spa |
dc.subject.keywords | Hirsutism | spa |
dc.subject.keywords | Obesity | spa |
dc.subject.keywords | Anovulation | spa |
dc.subject.keywords | Polycystic ovaries | spa |
dc.subject.keywords | Infertility | spa |
dc.subject.keywords | Menstrual cycle | spa |
dc.publisher.program | Ginecología y obstetricia | spa |
dc.creator.degreename | Especialista en Ginecología y obstetricia | spa |
dc.subject.decs | GINECOLOGIA | spa |
dc.subject.decs | SINDROME DEL OVARIO POLIQUISTICO | spa |
dc.subject.decs | ENDOCRINOLOGIA | spa |
dc.subject.decs | CICLO MESTRUAL | spa |
dc.description.degreelevel | Especialización | spa |
dc.publisher.faculty | Facultad de Medicina | spa |
dc.type.driver | info:eu-repo/semantics/bachelorThesis | spa |
dc.rights.creativecommons | Attribution-NonCommercial-NoDerivatives 4.0 International | spa |
dc.relation.references | 1. Balen A, Morley L, Misso M, Franks S, Legro R, Wijeyaratne C et al. The management of anovulatory infertility in women with polycystic ovary syndrome: an analysis of the evidence to support the development of global WHO guidance. Human Reproduction Update. 2018;22(6):687-708. DOI: 10.1093/humupd/dmw025 | spa |
dc.relation.references | 2. Tang T., Lord J.M., Norman R.J., et al: Insulin-sensitising drugs (metformin, rosiglitazone, pioglitazone, D-chiro-inositol) for women with polycystic ovary syndrome, oligo amenorrhoea and subfertility. Cochrane Database Syst Rev 2010; undefined. DOI: 10.1002/14651858.CD003053.pub6 | spa |
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dc.relation.references | Broekmans F, Knauff E, Valkenburg O, Laven J, Eijkemans M, Fauser B. PCOS according to the Rotterdam consensus criteria: change in prevalence among WHO-II anovulation and association with metabolic factors. BJOG: An International Journal of Obstetrics & Gynaecology. 2006;113(10):1210-1217. DOI: 10.1111/j.1471-0528.2006.01008.x | spa |
dc.relation.references | Dorn C, Mouillet J, Yan X, Ou Q, Sadovsky Y. Insulin enhances the transcription of luteinizing hormone-β gene. American Journal of Obstetrics and Gynecology. 2004;191(1):132-137. DOI: 10.1016/j.ajog.2004.01.054 | spa |
dc.relation.references | Ehrmann D, Liljenquist D, Kasza K, Azziz R, Legro R, Ghazzi M. Prevalence and Predictors of the Metabolic Syndrome in Women with Polycystic Ovary Syndrome. The Journal of Clinical Endocrinology & Metabolism. 2006;91(1):48-53. DOI: 10.1210/jc.2005-1329 | spa |
dc.relation.references | Lawson M.A., Jain S., Sun S., et al: Evidence for insulin suppression of baseline luteinizing hormone in women with polycystic ovarian syndrome and normal women. J Clin Endocrinol Metab 2008; 93: pp. 2089-2096. doi: 10.1210/jc.2007-2656 | spa |
dc.relation.references | Lizneva D, Suturina L, Walker W, Brakta S, Gavrilova-Jordan L, Azziz R. Criteria, prevalence, and phenotypes of polycystic ovary syndrome. Fertil Steril. 2016 Jul;106(1):6-15. doi: 10.1016/j.fertnstert.2016.05.003. Epub 2016 May 24. PMID: 27233760 | spa |
dc.relation.references | Moghetti P, Tosi F, Bonin C, Di Sarra D, Fiers T, Kaufman JM, Giagulli VA, Signori C, Zambotti F, Dall'Alda M, Spiazzi G, Zanolin ME, Bonora E. Divergences in insulin resistance between the different phenotypes of the polycystic ovary syndrome. J Clin Endocrinol Metab. 2013 Apr;98(4):E628-37. doi: 10.1210/jc.2012-3908. Epub 2013 Mar 8. PMID: 23476073 | spa |
dc.relation.references | Barriga P P, Ambrosi Penazzo N, Franco Finotti M, Celis AA, Cerdas O, Chávez JA, Cuitiño LA, Fernandes CE, Plata MA, Tirán-Saucedo J, Vanhauwaert PS. At 10 years of chlormadinone use in Latin America: a review. Gynecol Endocrinol. 2016 Jul;32(7):517-20. doi: 10.3109/09513590.2016.1153059 | spa |
dc.relation.references | de Bastos M, Stegeman BH, Rosendaal FR, Van Hylckama Vlieg A, Helmerhorst FM, Stijnen T, Dekkers OM. Combined oral contraceptives: venous thrombosis. Cochrane Database Syst Rev. 2014 Mar 3;(3):CD010813. doi: 10.1002/14651858.CD010813.pub2. PMID: 24590565. | spa |
dc.relation.references | Fraison E, Kostova E, Moran LJ, Bilal S, Ee CC, Venetis C, Costello MF. Metformina versus la píldora anticonceptiva oral combinada para el hirsutismo, el acné y el patrón menstrual en el síndrome de ovario poliquístico. Base de datos Cochrane de revisiones sistemáticas 2020, número 8. Art. No .: CD005552. DOI: 10.1002 / 14651858.CD005552.pub3. | spa |
dc.relation.references | Costello M, Shrestha B, Eden J, Sjoblom P, Johnson N. Insulin-sensitising drugs versus the combined oral contraceptive pill for hirsutism, acne and risk of diabetes, cardiovascular disease, and endometrial cancer in polycystic ovary syndrome. Cochrane Database Syst Rev. 2007 Jan 24;(1):CD005552. doi: 10.1002/14651858.CD005552.pub2. Update in: Cochrane Database Syst Rev. 2020 Aug 13;8:CD005552. PMID: 17253562 | spa |
dc.subject.proposal | Hirsutismo | spa |
dc.subject.proposal | Obesidad | spa |
dc.subject.proposal | Anovulación | spa |
dc.subject.proposal | Ciclo menstrual | spa |
dc.subject.proposal | Ovarios poliquísticos | spa |
dc.subject.proposal | Infertilidad | spa |
dc.publisher.grantor | Universidad Militar Nueva Granada | spa |
dc.type.coar | http://purl.org/coar/resource_type/c_7a1f | * |
dc.type.hasversion | info:eu-repo/semantics/acceptedVersion | spa |
dc.identifier.instname | instname:Universidad Militar Nueva Granada | spa |
dc.identifier.reponame | reponame:Repositorio Institucional Universidad Militar Nueva Granada | spa |
dc.identifier.repourl | repourl:https://repository.unimilitar.edu.co | spa |
dc.rights.local | Acceso abierto | spa |
dc.coverage.sede | Medicina | spa |
dc.rights.coar | http://purl.org/coar/access_right/c_abf2 |