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dc.contributor.advisorArbelaez Arbelaez, William Rafaelspa
dc.contributor.authorValiente Ortega, Michel
dc.contributor.authorVallejo, Pablo
dc.coverage.spatialMedicinaspa
dc.date.accessioned2015-10-19T15:03:10Z
dc.date.accessioned2019-12-30T18:59:50Z
dc.date.available2015-10-19T15:03:10Z
dc.date.available2019-12-30T18:59:50Z
dc.date.issued2015-08-12
dc.identifier.urihttp://hdl.handle.net/10654/6706
dc.description.abstractLas infecciones periprotésicas (IPP) constituyen una complicación devastadora en los procedimientos de reemplazo articular de cadera, con un aumento importante de las comorbilidades y de la mortalidad de nuestros pacientes, adicionalmente los procedimientos de revisión, generan riesgos superiores de IPP. Medidas preventivas y de tratamiento han venido siendo utilizadas recientemente para disminuir los riesgos de infección, y como manejo de esta complicación; entre estas la utilización de vehículos reabsorbibles para liberación local de antibiótico, coadyuvando el tratamiento sistémico antimicrobiano. Dentro de este tipo de sustitutos óseos encontramos el sulfato de calcio, con bien conocidas propiedades biológicas de osteoconducción, siendo el STIMULAN® (Biocomposites, Keele, UK) un sulfato de calcio sintético hemihidratado utilizado en el ámbito del tratamiento de defectos óseos, osteomielitis y procedimientos de artroplastia. Por su capacidad Osteoconductiva, al ser completamente reabsorbido y sustituido por hueso nuevo en lechos esqueléticos, además de sus posibles reacciones transitorias de citotoxicidad, nos planteamos la interrogante de su efecto secundario en osificaciones heterotópicas periarticulares. Este estudio describe los resultados radiográficos orientados a clasificar las osificaciones heterotópicas en pacientes sometidos a procedimiento de revisión de reemplazo total de cadera con utilización de STIMULAN® impregnado con antibiótico durante el cierre.spa
dc.formatpdfspa
dc.language.isospaspa
dc.publisherUniversidad Militar Nueva Granadaspa
dc.titleOsificaciones heterotópicas en revisión de reemplazo total de cadera, con aplicación durante el cierre de sulfato de calcio impregnado con antibiótico (stimulan®), en el Hospital Militar Central desde 2010 hasta 2014.spa
dc.typeinfo:eu-repo/semantics/bachelorThesisspa
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.subject.lembPROTESIS DE CADERAspa
dc.subject.lembARTROPLASTIA DE REEMPLAZO DE CADERAspa
dc.subject.lembPROCEDIMIENTOS ORTOPEDICOSspa
dc.subject.lembARTRITIS INFECCIOSAspa
dc.publisher.departmentFacultad de Medicinaspa
dc.type.localTrabajo de gradospa
dc.description.abstractenglishPeriprosthetic infections (IPP) are a devastating complication in hip joint replacement procedures, with a significant increase of comorbidities and mortality in our patients. In addition, revision procedures generate higher risks of IPP. Preventive and treatment measures have recently come to be used to reduce the risk of infection, and how to manage this complication; among these the use of resorbable vehicles for local release of antibiotic, contributing to the antimicrobial systemic treatment. Within this type of bone substitutes are calcium sulfate, with well-known biological properties of osteoconduction, being STIMULAN® (Biocomposites, Keele, UK) a synthetic calcium sulfate hemihydrate used in the field of treatment of bone defects, osteomyelitis and arthroplasty procedures. Due to its osteoconductive capacity, it is completely resorbed and replaced by new bone in skeletal beds, and along with its possible transient reaction of cytotoxicity, we raised the question of its secondary effect on periarticular heterotopic ossification. This study describes the radiographic results oriented to classify heterotopic ossification in patients undergoing revision procedure of total hip replacement with STIMULAN® impregnated with antibiotic during closing. Keywords: periprosthetic infections, total hip replacement revision, calcium sulfate vehicles, local release of antibiotic, heterotopic ossification.eng
dc.title.translatedHeterotopics Osifications in revision surgery of total hip arthroplasty, with the aplication of Stimulan during the wound closure, performed in the Hospital Militar, since 2010 to 2014spa
dc.subject.keywordsperiprosthetic infectionsspa
dc.subject.keywordstotal hip replacement revisionspa
dc.subject.keywordscalcium sulfate vehiclesspa
dc.subject.keywordslocal release of antibioticspa
dc.subject.keywordsheterotopic ossificationspa
dc.publisher.programCirugía Reconstructiva de Reemplazo Articular de Cadera y Rodillaspa
dc.creator.degreenameEspecialista en Cirugía Reconstructiva de Reemplazo Articular de Cadera y Rodillaspa
dc.relation.referencesBibliografía 1. National Hospital Discharge Survey. Survey results and products. Available at Center for Disease Control and Prevention, Atlanta (2009) 2. UK National Joint Registry 3. Kurtz, K. Ong, E. Lau, F. Mowat, M. Halpern. Projections of primary and revision hip and knee arthroplasty in the United States from 2005 to 2030. J Bone Joint Surg Am, 89 (4) (2007), pp. 780–785 4. Clohisy JC, Calvert G, Tull F, McDonald D, Maloney WJ. Reasons for revision hip surgery: a retrospective review. Clin Orthop Relat Res. 2004 Dec;(429):188-92. 5. Kurtz SM, Lau E, Schmier J, Ong KL, Zhao K, Parvizi J. Infection burden for hip and knee arthroplasty in the United States. J Arthroplasty. 2008 Oct;23(7):984-91. 6. T.P. Sculco. The economic impact of infected joint arthroplasty. Orthopedics, 18 (9) (1995), pp. 871–873 7. Workgroup Convened by Musculoskeletal Infection Society. New definition for periprosthetic joint infection. J Arthroplasty, 26 (8) (Dec 2011), p. 1136 8. 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Ectopic ossification: a complication after total hip replacement (author’s transl) [in German]. Arch Orthop Unfallchir. 1973;77(2):108-131 19. H.W. Buchholz, H. Engelbrecht. Über die Depotwirkung einiger Antibiotika bei Vermischung mit dem Kunstharz Palacos. Chirurg, 41 (1970), pp. 511–515 20. L.F. Peltier. The use of Plaster of Paris to fill defects in bone. Clin Orthop, 21 (1961), pp. 1–29 21. A.S. Coetzee, Regeneration of bone in the presence of calcium sulfate, Arch Otolaryngo, 106 (1980), pp. 405–409 22. Strauss A. Lokaler Antibiotikumträger aus Kalziumsulfat: Verträglichkeit im Gewebe und Pharmakokinetik der angewendeten Antibiotika nach Implantation in Kaninchen. Biomaterialien in der Medizin. Giessen: Köhler; 1999. p. 105–8. 23. G.H. Lee, J.G. Khoury, J.E. Bell, J.A. Buckwalter. adverse reactions to OsteoSet bone graft substitute, the incidence in a consecutive series. Iowa Orthop J, 22 (2002), pp. 35–38 24. D. Robinson, D. Alk, J. Sandbank, R. Farber, N. Halperin. Inflammatory reactions associated with a calcium sulfate bone substitute. Ann Transpl, 4 (1999), pp. 91–97 25. Petrova. Gipsfüllung von Knochenhöhlen bei Osteomyelitis. Zentralorg Ges Chir, 43 (1928), p. 485 26. V. Dacquet, A. Varlet, R.N. Tandogan, M.M. Tahon, L. Fournier, F. Jehl, H. Monteil, G. Bascoulergue. Antibiotic-impregnated Plaster of Paris beads—trials with teicoplanin. Clin Orthop, 282 (1992), pp. 241–249 27. Turner TM, Urban RM, Gitelis S, Sumner DR, Haggard WO, Parr JE. Antibiotic delivery from calcium sulfate as a synthetic bone graft. Fourth Combined Meeting of the American and European Musculoskeletal Tumor Societies, 1998. Washington, DC. 28. M. McKee, L. Wild, E. Schemitsch, J. Waddell. The use of an antibiotic-impregnated, osteoconductive, bioabsorbable bone substitute in the treatment of infected long bone defects: early results of a prospective trial. J Orthop Trauma, 16 (2002), pp. 622–627 29. Arbeláez W, Farias P, Suescun J. Osificaciones heterotopicas, en pacientes sometidos a reemplazo total de cadera primario mediante abordaje lateral indirecto modificado, en el hospital militar central de Bogotá en los años 2005-2008. http://repository.unimilitar.edu.co/bitstream/10654/10323/2/ArbelaezWilliam2011.pdfspa
dc.subject.proposalInfecciones periprotésicasspa
dc.subject.proposalRevisión de reemplazo total de caderaspa
dc.subject.proposalVehículos de sulfato de calciospa
dc.subject.proposalLiberación local de antibióticospa
dc.subject.proposalOsificaciones heterotópicasspa


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